glycolic acid

noun

gly·​col·​ic acid (ˌ)glī-ˈkä-lik- 

variants or glycollic acid

: an alpha hydroxy acid C₂H₄O₃ found especially in unripe grapes and sugar beets and used especially in textile and leather processing and in skin-care treatments especially as an exfoliant

Examples of glycolic acid in a Sentence

Recent Examples on the Web

Infused with glycolic acid, it’s designed with mature skin in mind—but anyone chasing that plump, bouncy glow will appreciate it. —Christa Joanna Lee, Allure, 28 Aug. 2025

For our tester with an oily T-zone and blemishes, this glycolic acid toner from The Inkey List made a lasting impression. —Jamie Allison Sanders, People.com, 21 Aug. 2025

The pointed applicator offers precise application, ensuring its blend of glycolic acid, BHAs, and PHAs can eliminate flaking and reduce surface oils. —Conçetta Ciarlo, Vogue, 1 Aug. 2025

The combination of salicylic acid and glycolic acid help decongest pores without stripping your barrier. —Jenifer Calle, Glamour, 5 June 2025

Word History

Etymology

International Scientific Vocabulary glycol + -ic entry 1

First Known Use

1852, in the meaning defined above

Rhymes for glycolic acid

• antacid
• placid

Medical Definition

glycolic acid

noun

variants also glycollic acid

: an alpha hydroxy acid C₂H₄O₃ that is oxidized to glyoxylic acid in photosynthesis, is used as an agent to produce chemical peels in cutaneous rejuvenation treatments, and is the major toxic metabolite in ethylene glycol poisoning

called also hydroxyacetic acid